Manchester United face Paris Saint-Germain and Chelsea take on Lille

  Manchester United face Paris Saint-Germain and Chelsea take on Lille

Ralf Rangnick’s Man United take on PSG in the pick of the Champions League fixtures, with long-time rivals Cristiano Ronaldo and Lionel Messi set to meet yet again.

Last season’s runners-up and current Premier League leaders Manchester City meet Europa League winners Villarreal, while Liverpool will fancy their chances against Red Bull Salzburg.

Last season’s runners-up and current Premier League leaders Manchester City meet Europa League winners Villarreal, while Liverpool will fancy their chances against Red Bull Salzburg.

Elsewhere, Bundesliga champions Bayern Munich face La Liga title winners Atletico Madrid, Italian giants Inter Milan take on in-form Ajax and Sporting meet Juventus.

Real Madrid, who are bidding to win the Champions League for a record 14th time, begin the knockout stages against Portuguese outfit Benfica.

PSG and Manchester United have met four times in the Champions League since 2018 and Mauricio Pochettino has been tipped to succeed Rangnick in the Old Trafford hot-seat at the end of the season.